Background
The thyroid gland produces thyroid hormones which play an important role in the metabolism and proliferation of blood cells. functional disorders of thyroid gland can cause disruption of thyroid hormone excretion and give a different effect on the components of blood cells, thus causing conditions of anemia, leukopenia, erythrocytosis, and thrombocytopenia. Even in some cases, even though it is very rare to report pancytopenia associated with thyroid gland dysfunction. Effects of thyroid hormones It was also known to affect the RBC index including MCV, MCH and MCHC in this study looking for differences in blood components in various hyper, hypo and normothyroid conditions.
Purpose
To determines the diferrences of blood component in various thyroid hormone levels
Methods
This study was conducted by collecting medical records in the private endocrine outpatient clinic during January-February 2019. Involved total 43 secondary data consisting of 5 (11.6%) male and 38 (88.4%) female. They were diagnosed with a thyroid gland disorder for the first time. Based on Thyroid hormones level, the samples were then classified according to hyperthyroidism, hypothyroidism and normothyroidism
Results
The average Haemoglobin, platelet, MCH and MCHC values were higher in the hypothyroid group. Whereas for the average Erythrocytes was higher in the hyperthyroid group and WBC was higher in the normothyroid group.
There were significant differences in levels of haemoglobin, WBC, and MCHC in all three groups of thyroid hormones. whereas for platelets there was no statistically significant difference in the three groups
There was a significant difference in MCHC value between hyper-hypothyroid patients and normo-hypothyroid. The relationship between FT4 and Haemoglobin, MCV, and MCHC is negative. The relationship between FT4 and erythrocytes and MCH did not show a significant relationship
Conclusion
There were some differences in blood cell count component between various thyroid hormone status