Neuroendocrine tumours (NETs) are characterized by the presence of neurosecretory granules and most commonly include tumours of the intestine (carcinoids), endocrine pancreas, lung, thymus, adrenal medulla, paraganglia, thyroid C cells, parathyroid and pituitary gland. Due to the heterogenous location and behaviour of NETs, they are best managed in a multidisciplinary setting. The role of the endocrinologist within this team includes: 1. diagnosis and treatment of functioning NETs; 2. diagnosis, longitudinal follow-up and appropriate genetic triage of heritable NET syndromes (multiple endocrine neoplasia (MEN) syndromes 1 and 2, von Hippel Lindau, hereditary paraganglioma syndromes); and 3. management of endocrine complications of treatment, in particular diabetes mellitus. This presentation will focus on specific endocrine presentations of NETs including functioning pancreatic NETs, MEN1 and carcinoid crises.