Tuesday, 20th August ESA-SRB-AOTA 2019

This session is sponsored by

This session is sponsored by

This session is sponsored by

The conference acknowledges the support of

• Iodine Deficiency and Iodine Excess: What are the Implications for Thyroid Health? - Angela Leung

The conference acknowledges the support of

• Dissecting the contribution of androgen-mediated mechanisms in driving endocrine, reproductive and metabolic traits of polycystic ovary syndrome (PCOS)  - Kirsty Walters

The conference acknowledges the support of

• The metabolic and developmental impact of murine embryo culture in a novel microfluidic device  - Paul McKeegan
• Novel insights into TGFβ superfamily regulation of FSH synthesis  - Daniel Bernard

• RUNX1 as a potential co-regulator of progesterone receptor in mouse peri-ovulatory granulosa cells - Thao Dinh
• Regulation of nuclear gene expression by mitochondria in oocyte - Deepak Adhikari
• Nicotinamide mononucleotide alleviates hepatic steatosis and insulin resistance in the DHT-induced PCOS mice model. - Ali Aflatounian
• Proteomic and functional analysis of the human fallopian tube matrisome  - Yazmin Brown

The conference acknowledges the support of

• Sperm cryopreservation prior to gonadotoxic treatment: experience of a single academic centre over 4 decades - Nandini Shankara Narayana

• Treatment of advanced thyroid cancers - Hang-Seok Chang
• Active surveillance for papillary thyroid microcarcinoma - Tomohiko Nakamura
• Management of Medullary Thyroid Cancer in 2019 and beyond - Bruce Robinson

• A novel point of vulnerability in male development  - Josephine Bowles
• Disorders of Sex Development in Adolescence  - Jenny Batch
• Clinical and ethical challenges of gonadectomy in children and adolescents with DSD – for whom, when, why (and why not)?  - Michele O'Connell
• Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9 - Andrew H Sinclair

• Tissue specific regulation of gene expression in endometrium and association with reproductive pathologies - Grant W. Montgomery
• Genetics of Mayer-Rokitansky-Kuster-Hauser syndrome: role of Hnf1b in Mullerian duct development - Emanuele Pelosi
• Oestrogenic actions on the endometrium are mediated through β-catenin  - Isabella G Moore
• Quantification and clonogenicity of stem/progenitor cells in menstrual fluid from healthy women - Caroline E Gargett

• Big GIGnormous TERrific Placenta Data  - Claire Roberts
• New insights into ovarian development and function  - Dagmar Wilhelm
• Next generation sequencing of a large international cohort of patients with Disorders/Differences of Sex Development reveals diagnostic and novel genetic variants  - Katie Ayers
• Opportunities and challenges in analysis of emerging datasets for reproductive genomics  - Grant Montgomery

The conference acknowledges the support of

• High-resolution 4D live-oocyte imaging identifies a new model of asymmetric division - Jessica Greaney
• Granulosa cell transcriptome of neonatal mice provides new clues for primordial follicle activation - Emmalee A Ford
• The roles of TGFβ superfamily ligands in gonocyte fate choices - Sarah C Moody
• Heparan sulphate: Regulator of growth differentiation factor 9 (GDF9) signalling during oocyte maturation - Darren JX Chow

Lunch served outside of room for attendees

12:30pm: Opening of ECR workshop

12:30-12:40: Kelly Walton

12:40-12:50: Andy Pask

12:50-1:00: Jenny Gunton

1:00-1:10: Tu'uhevaha Kaitu'u-Lino

1:10-1:30: Panel discussion

Lunch served outside of room for attendees

• Binding affinities of high and low affinity corticosteroid-binding globulin; effect of fever and acidosis. - Emily J Meyer
• ADT in prostate cancer patients: the benefits of a 12-month home-based progressive resistance training program   - Teresa Lam
• Associations between reproductive factors and bone health outcomes in women with diabetes: a 15-year longitudinal study - Eleanor P Thong
• Understanding Bone Fragility in Adults with Cerebral Palsy through Longitudinal Analysis - Anne Trinh
• Parental multiple endocrine neoplasia type 1 (MEN 1) is associated with increased offspring mortality postpartum: the impact of maternal MEN 1 and antenatal hypercalcemia - Michael Thompson

• Chronic activation of arcuate GABA neurons leads to reproductive dysfunction: potential implication for PCOS  - Elodie Desroziers
• Adverse effects of maternal stress on fetal neurosteroid levels and late gestation brain development - Jonathan J Hirst
• Kisspeptin neurons are central regulators of fertility and metabolism  - Jeremy Smith
• Sexual dimorphism in the control of body weight and metabolic function in healthy men and women  - Belinda Henry

The conference acknowledges the support of

• Global deletion of glucocorticoid receptor increases placental weight and impairs placental hemodynamic function in late gestation in the mouse - Emma N Panting
• New generation antiplatelet drugs for prevention of pre-eclampsia: novel roles in regulating maternal vascular constriction - Natasha de Alwis
• A placenta-specific protease that is critical for trophoblast syncytialization - Mary Mansilla
• Lipopolysaccharide induced inflammation in choriodecidual explants is sex dependent - Sarah J Delforce
• The effect of commonly used antipsychotics and benzodiazepines on placental viability and function.  - Roxanne Hastie
• Angiotensin converting enzyme 2 (ACE2) and pregnancy complications: preeclampsia and small for gestational age. - Sonia Tamanna

• Non-coding RNAs as therapeutics in cancer – dawn of a new era - Peter J Leedman
• Elf5 and endocrine resistance in breast cancer  - Christopher Ormandy
• The highs and lows of androgen signalling in prostate cancer - Renea A Taylor
• Untangling the complex relations between hormones, obesity and risk of ovarian and endometrial cancer  - Penelope Webb

• Application of Deep Learning to the Diagnosis of Cervical Lymph Node Metastasis from Thyroid Cancer with CT: External Validation and Clinical Utility in Resident Training - Eun Ju Ha
• Rapid detection of papillary thyroid carcinoma by fluorescence imaging using a γ-glutamyltranspeptidase-specific probe: A pilot study - Rumi Hino
• Computer-aided diagnosis system for evaluation of thyroid nodules on ultrasonography: prospective non-inferiority study according to the experience level of radiologists - Sae Rom SR Chung
• Integrated thyroid nodule risk stratification using BTA U (ultrasound) and Thy (cytology): outcomes at a large tertiary centre.  - Christopher W Rowe
• Comparison of Three International guidelines of Concordance of Ultrasonography Classified Nodules and Impact of Biopsy Size Thresholds on Diagnostic Performance. - Younghee Yim
• Lymph node metastases detection by serum thyroglobulin and neck ultrasonography, and long term follow up in patients with papillary or follicular thyroid cancer previously treated with radioiodine and/or surgery   - Alessandro Antonelli
• Appropriate frequency and interval of follow-up ultrasonography (FUUS) surveillance during the first 10 years after total thyroidectomy (TT) in patients with papillary thyroid carcinoma (PTC) - Yoo Jin Lee
• Malignancy risk assessment using ultrasonography patterns in each cytology categories: Korean-Thyroid Imaging Reporting and Data System (TIRADS) vs American College of Radiology-TIRADS - Sunyoung Kang

• Aurora Kinases Regulate Telomerase in Thyroid Cancer - Grace Lim
• Disruption of thyroid hormone receptor action in the cerebellar Purkinje cell impaired long-term plasticity - Noriyuki Koibuchi
• Diallyl trisulfide induces anaplastic thyroid carcinoma 8505C cells apoptosis by ATM-mediated DNA damage - Huixin Yu
• Targeting TERT activation with mTOR inhibitors in thyroid cancer - Martyn Bullock
• Molecular profiling thyroid cancer; targeted therapies and personalised medicine - Matti Gild
• Punicalagin induces senescence growth arrest in human papillary thyroid carcinoma BCPAP cells via NF-κB signaling pathway - Jiandong Bao
• MKL1 overexpression predicts poor prognosis in patients with papillary thyroid cancer and promotes nodal metastasis through TGF-β/Smad3/MMP2 pathway - Xian Cheng
• Study on the relationship between hyperthyroidism and vascular endothelial cell damage in human, rat and cell - Peng Liu

The conference acknowledges the support of

• Inhibin and Activin: From Reproduction to Metabolism - Kelly Walton

The conference acknowledges the support of

• High-throughput screen identifies new hormone alternative contraceptive - Alaknanda Alaknanda
• Epididymal CRISPs regulates efficient flagellar waveform and optimal sperm function - Avinash S. Gaikwad
• Deliverable transgenics can be used to rescue infertility in Sertoli cell androgen receptor knock-out mice. - Annalucia Darbey
• Macrophages mediate uterine vascular remodelling required to establish pregnancy in mice - Holly M Groome
• The small non-coding RNA profile of mouse oocytes is modified during ageing - Bettina P Mihalas
• Determining the role of PRC2 in female germline epigenetic programming and offspring health - Ellen Jarred

• Real-world experience with lenvatinib for radioactive iodine refractory differentiated thyroid carcinoma with analyses of prognostic biomarkers for survival outcomes: Korean multicenter study - Eyun Song
• Multimodality treatment improves loco-regional control and overall survival in patients with anaplastic thyroid cancer - Venessa Tsang
• Lenvatinib for radioiodine refractory thyroid cancer: real-world experience in southern Taiwan - Yen-Hsiang Chang
• Redifferentiation therapy for metastatic follicular / poorly differentiated thyroid cancer utilising I124 PET/CT scan  - Michael Mond
• A retrospective evaluation of the benefits of radioiodine therapy for metastatic poor differentiated thyroid cancer - Yasushi Noguchi
• Detection of Metastatic Sporadic Medullary Thyroid Carcinoma using PET/CT with Radiolabelled Gastrin Analogue - Rinky Giri

• Gender- and age- differences of seasonal changes in thyroid function in healthy subjects in Japan - Sayaka Yamada
• The relationship between population’s iodine status, thyroid function and water iodine in China - Peng L Liu
• A unique training model in the management of Thyroid disorders for Primary care Physicians (PCPs) in India - Deepak Monga
• Free T3 but not Free T4, is associated with brown adipose tissue and metabolic rate in healthy young adults - Lijuan Sun
• Radiofrequency Ablation of Primary Parathyroid Adenoma: Preliminary Results for Patients Ineligible for Surgery - Eun Ju Ha
• Sonographic Evolution of Benign Nonfunctioning Thyroid Nodules After Ultrasound Guided Microwave Ablation - Shuhang Xu
• Oral liquid L-thyroxine (L-T4) treatment in patients thyroidectomized for thyroid cancer (without malabsorption) - Poupak Fallahi